Low-dose naltrexone

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Naltrexone is known as a pure opiate receptor antagonist. This means that it can block the effects of opiate medications (feelings of well being and pain relief). Naltrexone stops people wanting to take opiate medications and has a similar effect on alcohol cravings. 

Naltrexone has been used since the 1970’s in Australia for treatment of opioid and alcohol dependency at a dose of 50mg a day. 

Lower doses (typically 4.5mg or below) have been researched in the treatment of autoimmune conditions. It has a history of use in MS, fibromyalgia, crohn’s disease and pain management. It works by occupying the opiate receptor for a few hours at night, resulting in increased endorphin production and an immunomodulatory and anti-inflammatory response. Low dose naltrexone is still considered experimental by the medical profession due to the lack of robust clinical trial data and is prescribed “off licence” by doctors with experience in this area.